Thus, the possible role of carnosine could be prevention of skeletal muscle acidity in improving exercise performance. Antioxidant function, muscle contractility regulation, and pH buffering, are the possible physiological roles of carnosine in skeletal muscle. and Harris et al., showed that 28 days of β-alanine supplementation increased intramuscular levels of carnosine by nearly 60%.
Carnosine (β-alanyl-L-histidine) is the main histidine-containing dipeptide in humans. There are many cellular pH buffers defend against exercise-induced acidosis, which include phosphocreatine, inorganic phosphates and histidine-containing dipeptides.
On the other hand, it has been shown that large amounts of H + are produced in the muscles during high-intensity exercise and result in pH reduction. Among them, β-alanine supplementation has been suggested to improve performance during high-intensity exercises.
Ingestion of some amino acids has presumable roles in performance improvement in athletes.
